Rejuvalife Vitality Institute
Beverly Hills CA

Diabetes Medication May Decrease BMI in Obese Teens

The obesity rate among children has tripled since 1960, with 32% of US children considered overweight or obese, and many of them suffering the same weight-related problems as adults: diabetes mellitus type 2, hypertension and cardiovascular disease.  In the February issue of Archives of Pediatrics & Adolescent Medicine, a report by Darrell M. Wilson, M.D., of Stanford University and the Lucile S. Packard Children’s Hospital, Stanford, Calif., along with colleagues in the Glaser Pediatric Research Network Obesity Study Group showed that teens given Metformin, a common pill given to type 2 diabetics, helped lower their BMI score. BMI is an indicator of body fat percentage—the lower your BMI the less risk you have for cardiovascular disease and other weight-related disorders.

The research group split 77 obese teenagers, ages 13 to 18, into two groups. Both groups were put on a “lifestyle intervention program” which included dietary changes and increased physical activity. One group received 2,000 mg of Metformin XR per day and the other group received a placebo. After 38 weeks, the kids receiving the Metformin XR showed a significantly lowered BMI than the teens receiving the placebo, even though all the teens were on the same diet and exercise plan. Unfortunately, once the drug was discontinued, the BMI in the teens previously taking Metformin again went up. This certainly lends credence to my long-held belief that Metformin can be an effective weight-management tool for some people.

In addition to helping with weight problems, Metformin works very similarly to Resveratrol and has significant anti-aging properties. Like Resveratrol, it helps regulate the Sirt-2 gene, helping protect DNA from damage, so it’s a very important product.

I think Metformin can be a helpful treatment for kids who are overweight. It will improve insulin resistance which will assist with weight loss, which is a great thing! Many of these overweight young kids have developed insulin resistance, so many of them do need this extra boost. Metformin can actually help some overweight teens avoid the development of type 2 diabetes, when used in conjunction with diet and exercise.

It’s not a magic pill, and you still need diet and exercise to get the best results, but this combination certainly shows promise.

Ask Dr. Berger – What is “Fat Transfer”?

I was explaining our new Body-Jet procedure to a patient last week, and how one of the great things about the Body-Jet Liposculpture procedure was the ability to use the Body-Jet to harvest fat in near perfect condition for use in Fat Transfer procedures. The patient asked me why she would need or want to transfer fat – GOOD QUESTION!  I’ve posted the answer I gave her as the subject of my latest video:

If you have any further questions on this, or any other procedure or topic, feel free to post them here, on our Facebook page, or give the office a call at 877-REJUVMD.

Thanks for reading,

Andre Berger, M.D.

Excess Body Fat = Thousands of Cancer Cases Annually

A shocking new study was published last week by researchers with the American Institute for Cancer Research,  that states more than 100,000 cases of cancer are caused annually by excess body-fat and obesity. The researchers studied seven cancers with known links to obesity along with actual case counts that were likely obesity-related.

From

The report says that 49 percent of endometrial cancers are caused by excess body fat. That number is followed by 35 percent of esophageal cancer cases; 28 percent of pancreatic cancer cases; 24 percent of kidney cancer cases; 21 percent of gallbladder cancer cases; 17 percent of breast cancer cases; and 9 percent of colorectal cancer cases.

“This is the first time that we’ve put real, quantifiable case numbers on obesity-related cancers,” said Glen Weldon, the American Institute for Cancer Research educational director. In addition, he said, it’s not just causing cancer that’s an issue.

“Obesity not only raises the risk for getting cancer,” Weldon said. “It also has a negative effect on survival and can make treatment more difficult.” (Link to full story)

The sheer magnitude of this is a bit overwhelming, and calling attention to the problem is certainly necessary. In addition to cancer, we know obesity-related health problems abound, including heart disease, diabetes, high blood pressure, strokes and various other maladies. As I’ve explained before, increased body fat can lead to increased cellular inflammation, which is linked to DNA mutation and diseased cell growth, as is seen in cancers and many other diseases.

Unfortunately, the study doesn’t propose any solution. While some would suggest simply losing the weight, or not gaining it at all, I can’t help but add “keeping your soup clean” – i.e. not just counting calories, but eating a nutritionally dense and healthy diet and adopting an active lifestyle are paramount to good health.

Thanks for reading,

Andre Berger, M.D.

Related recent posts from the archives:

• Obesity Shrinks Your Brain & Shortens Your Life
• Is Your Soup Clean? Questions & Answers about Diagnostic Testing
• This is Your Brain on Junk Food
• Food Choices Supersede Genetics

Move Over BMI, Here Comes BCA

The Body Mass Index can't distinguish lean body mass from fat weight, therefore very muscular people have BMI scores of the morbidly obese. (image: How Things Work 2005)

Invented in the mid 19th century, the Body Mass Index, or BMI, is currently the most widely-used diagnostic tool for gauging whether a person is at a healthy weight, under or overweight, and is reached through a calculation of height and weight measurements.

A person’s BMI is a very simple indicator of a person’s “fatness” or “thinness” that when used as designed, allows doctors to more objectively discuss weight issues with their patients.  Using this calculation, doctors use an individual’s particular BMI to determine whether or not they need medical care for being over or underweight: a BMI of 18.5 to 25 usually indicates optimal weight, a BMI lower than 18.5 suggests the person is underweight, while a number above 25 may indicate the person is overweight; a BMI below 17.5 may indicate the person has anorexia nervosa or a related disorder; a number above 30 suggests the person is obese (over 40, morbidly obese).

There is some controversy over the accuracy of this measurement, as it can’t distinguish body fat from lean body mass,  therefore a very muscular person will weigh more, and therefore have a higher BMI, even though he/she may really be quite lean,  and many feel it is most appropriately used in the study of populations, not individuals, for that reason.

There is another method of measurement that, according to recent studies, is a more reliable indicator. Body Composition Analysis (BCA) measures four parameters of health.

The BCA for Weight Management helps us measure four parameters of health:
1. Body Hydration Status by measuring the cellular fluid.
2. Cell Health Status by measuring the lean body mass and fat mass.
3, Nutritional Status through the BIA meter.  (Bioelectrical Impedance Analyzer)
4. Longevity Status by calculating various indices.

From Medical News Today:

Recent studies using similar analysis suggest that up to 30% of obese people do not in fact require medical treatment. Widespread adoption of BCA could significantly improve the targeting of limited healthcare resources in the context of one of modern society’s global killers. Thanks to advances in imaging technology, variables – such as the body’s fat proportion, location and distribution and the size of fat cells and fat droplets within these cells – can now be factored into the health risk assessment.

Coupled with a better understanding of the interrelation between genes, environment, hormone levels and metabolism, BCA gives clinicians a clearer picture of the specific health risks to an individual.

In light of the growing evidence in favour of functional BCA, the authors conclude that “the definitions of both ‘overweight’ and ‘malnutrition’ should be reconsidered” by clinicians and researchers. Evidently, size does still matter but it’s what you do with it that really counts.

One way to ensure that you are at “optimal weight” regardless of how it’s measured is to…yep, stay active, eat a healthy diet, and keep your soup clean!

Thanks for reading,

Andre Berger, M.D.

p.s. Full disclosure – we have been using the BCA for Weight Management at Rejuvalife for quite some time. Give us a call if you’re interested in being measured!

Associated posts:

Keeping Your Soup Clean: Questions and Answers About Diagnostic Testing

Obesity Shrinks Your Brain & Shortens Your Life

Insulin Resistance Improved with Exercise

Weight Loss Improves Mood in Depressed Individuals

FDA Cracking Down on Misleading Nutrition Labels

Obesity Shrinks Your Brain & Shortens Your Life

Health professionals have known for decades about the severe health problems caused by obesity, and the cost of obesity to society and industry is a big part of the current health care debate.  Two recent studies shows, however, that the price of obesity to the patient is even higher than previously thought. In addition to increased risk of heart disease, Type 2 diabetes, hypertension and some cancers, the studies show that the negative effects of obesity include degeneration of the brain, and a shortened lifespan, as well.

In the first study, researchers concluded that the brains of obese people age more quickly than normal-weight people, as much as 16 years faster, researchers say, representing “severe brain degeneration”. Even moderately overweight people had “older” brains than their lean counterparts.(link)

A new study finds obese people have 8 percent less brain tissue than normal-weight individuals. Their brains look 16 years older than the brains of lean individuals, researchers said today.

Those classified as overweight have 4 percent less brain tissue and their brains appear to have aged prematurely by 8 years.

The results, based on brain scans of 94 people in their 70s, represent “severe brain degeneration,” said Paul Thompson, senior author of the study and a UCLA professor of neurology.

“That’s a big loss of tissue and it depletes your cognitive reserves, putting you at much greater risk of Alzheimer’s and other diseases that attack the brain,” said Thompson. “But you can greatly reduce your risk for Alzheimer’s, if you can eat healthily and keep your weight under control.”

“The brains of obese people looked 16 years older than the brains of those who were lean, and in overweight people looked 8 years older,” Thompson said.

(Full article from LiveScience)

The second study showed that the extremely obese will have shorter lives, and for obese smokers, this decrease is even more significant.

Extremely obese people — those who are 80 or more pounds over a normal weight — live three to 12 fewer years than their normal-weight peers, a new study shows.

Just being overweight or moderately obese, however, has little or no effect on life span, the research found. The finding adds to the growing body of evidence that being slightly overweight may have no influence on life expectancy, but being severely overweight trims years off people’s lives.

Economists with RTI International, a non-profit research organization in Research Triangle Park, N.C., analyzed national data on 366,000 people. Among the findings being published online in the journal Obesity:

•Overall, excess weight was responsible for the loss of roughly 95 million years of life in the USA in 2008.

•Non-smokers who are obese — those who are about 30 or more pounds over a healthy weight — have a shorter life span by a year or less.

•Non-smokers who are overweight — about 29 pounds over a healthy weight — do not have shortened lives.

•Smoking takes a toll, too, and very heavy smokers are affected most. An 18-year-old white male who is normal weight and does not smoke can expect to live to age 81. If he’s extremely obese and a smoker, his life expectancy is 60, a difference of 21 years.

The effect of extreme obesity appears to be greater for men than women and for whites than blacks, says Derek Brown, a health economist with RTI International and co-author of the study.
( Full article from USA Today)

Obesity is an epidemic. I cannot stress enough how important addressing this is to individual health and quality of life, as well as the good of society at large.

Overall, about 66% of adults in the USA are either overweight or obese. About one-third of people are in the obese category, meaning they have a body mass index of 30 or greater.

Body mass index, or BMI, is a measure based on height and weight. About 6% of people are extremely obese — that is, they have a BMI of 40 or greater.

There is no time like the present to adopt a healthier lifestyle, and if you or a loved one is obese, a visit to your doctor for a discussion on starting a medically managed weight management program should be a top priority.

Thanks for reading,

Andre Berger, M.D.